CD1A Mouse Monoclonal Antibody [A3F9]
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CD1A
Swiss Prot
P06126 Human
Cellular Locus
Cell membrane, endosome membrane, membrane raft.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human CD1A aa 50-250.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
K562 cell lysates, human skin tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:1,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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