Dynamin 1 Mouse Monoclonal Antibody [A1B1]
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
B dynamin antibody D100 antibody DNM 1 antibody DNM antibody DNM1 antibody DYN1_HUMAN antibody Dynamin antibody Dynamin-1 antibody Dynamin1 antibody
Abbreviation
DNM1
Swiss Prot
Q05193 Human, P39053 Mouse, P21575 Rat
Cellular Locus
Cytoskeleton, cytoplasm.
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human Dynamin 1 aa 500-800.
Isotype
IgM
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IHC-P, WB, IF-Cell
Positive Control
Rat brain tissue, mouse brain, SiHa, mouse brain tissue lysate, rat brain tissue lysate.
Concentration
2 mg/mL
Dilution
IHC-P: 1:1,000 ;WB: 1:1,000 ;IF-Cell: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 97 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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