MGST1 Mouse Monoclonal Antibody [14H2]
DNA replication licensing factor MCM7 is a protein that in humans is encoded by the MCM7 gene.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Microsomal glutathione S-transferase 1,Microsomal GST-1,Microsomal GST-I,MGST1
Swiss Prot
P10620 Human, Q91VS7 Mouse, P08011 Rat
Cellular Locus
Endoplasmic reticulum, Mitochondrion.
Host
Mouse
Species Reactivity
Human,Mouse,Rat,Zebrafish
Immunogen
Recombinant protein within Human MGST1 aa 1-144 / 155.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Concentration
2 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:200-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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