GRB2 Mouse Monoclonal Antibody [11-B11]

Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene. The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the sem-5 gene of Caenorhabditis elegans, which is involved in the signal transduction pathway.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Abundant SRC homology antibody Adapter protein GRB2 antibody ASH antibody Ash protein antibody EGFRBP GRB2 antibody Epidermal growth factor receptor binding protein antibody Epidermal growth factor receptor binding protein GRB2 antibody GRB 2 antibody GRB2 adapter protein antibody Grb2 antibody GRB2_HUMAN antibody Grb3 3 antibody Growth factor receptor bound protein 2 antibody Growth factor receptor bound protein 3 antibody Growth factor receptor-bound protein 2 antibody HT027 antibody MST084 antibody MSTP084 antibody NCKAP2 antibody OTTHUMP00000166096 antibody OTTHUMP00000166097 antibody OTTHUMP00000166098 antibody Protein ash antibody SEM5 antibody SH2/SH3 adapter GRB2 antibody

Abbreviation

GRB2, ASH

Swiss Prot

P62993 Human, Q60631 Mouse, P62994 Rat

Cellular Locus

Endosome, Nucleus, Golgi apparatus, Cytoplasm.

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human GRB2 aa 21-217 / 217.

Isotype

IgG2b

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

293T cell lysate, A431 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse testis tissue, rat testis tissue, rat brain tissue, MCF-7, HepG2.

Concentration

2 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 25 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

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