NaV1.7 Mouse Monoclonal Antibody [1D6]
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na (+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
hNE-Na, PN1, SCN9A, NENA
Swiss Prot
Q15858 Human
Cellular Locus
Cell membrane, Cell projection.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within Human NaV17 aa 1,577-1,626 / 1,988.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IHC-P, IF-Cell, FC, WB
Positive Control
A549, Hela, human colon cancer tissue, human kidney tissue.
Concentration
2 mg/mL
Dilution
IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:200;WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 226 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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