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MTERFD1 Mouse Monoclonal Antibody [A8-A10]

MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

CGI 12 antibody mitochondrial antibody Mitochondrial transcription termination factor 3 antibody MTER1_HUMAN antibody MTERF domain containing 1 antibody mTERF domain containing protein 1 mitochondrial antibody mTERF domain-containing protein 1 antibody mTERF3 antibody Mterfd1 antibody Transcription termination factor 3, mitochondrial antibody

Abbreviation

mTERF3, MTERF3, MTERFD1, CGI-12

Swiss Prot

Q96E29 Human, Q8R3J4 Mouse

Cellular Locus

Mitochondrion.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein with Human MTERFD1 aa 29-417 / 417.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

HeLa cell lysate, HepG2 cell lysate, K-562 cell lysate, HEK-293 cell lysate, SH-SY5Y cell lysate, SK-OV-3 cell lysate, human liver tissue, A431.

Concentration

2 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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