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CD271 Rabbit Polyclonal Antibody

NGFR p75 or CD271 is a 75kD transmembrane glycoprotein consisting of an extracellular domain which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain, and a cytoplasmic domain. NGFR p75 displays paradoxical functions when acting alone or with other receptor proteins. Working in concert with Trk receptors, it recognizes neurotrophins and transmits trophic signals into the cell. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

CD271 antibody CD271 antigen antibody Gp80 LNGFR antibody Gp80-LNGFR antibody Low affinity nerve growth factor receptor antibody Low affinity neurotrophin receptor p75NTR antibody Low-affinity nerve growth factor receptor antibody Nerve growth factor receptor antibody Nerve growth factor receptor TNFR superfamily member 16 antibody NGF receptor antibody Ngfr antibody p75 ICD antibody p75 Neurotrophin receptor antibody p75 NTR antibody p75 (NTR) antibody p75NTR antibody TNFR Superfamily Member 16 antibody TNFRSF16 antibody TNR16_HUMAN antibody Tumor necrosis factor receptor superfamily member 16 antibody

Abbreviation

NGF receptor

Swiss Prot

Q9Z0W1 Mouse, P07174 Rat

Cellular Locus

Cell membrane, Perikaryon, Cell projection, growth cone, Cell projection, dendritic spine.

Host

Rabbit

Species Reactivity

Mouse,Rat

Immunogen

Synthetic peptide corresponding to Mouse CD271 aa 91-140 / 427 mouse.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

F9 cell lysate, PC-12 cell lysate, RAW264.7 cell lysate, L6.

Concentration

1 mg/mL

Dilution

WB: 1:2,000-1:5,000 ;IF-Cell: 1:50

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 46 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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