CD271 Rabbit Polyclonal Antibody
NGFR p75 or CD271 is a 75kD transmembrane glycoprotein consisting of an extracellular domain which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain, and a cytoplasmic domain. NGFR p75 displays paradoxical functions when acting alone or with other receptor proteins. Working in concert with Trk receptors, it recognizes neurotrophins and transmits trophic signals into the cell. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
NGF receptor
Swiss Prot
Q9Z0W1 Mouse, P07174 Rat
Cellular Locus
Cell membrane, Perikaryon, Cell projection, growth cone, Cell projection, dendritic spine.
Host
Rabbit
Species Reactivity
Mouse,Rat
Immunogen
Synthetic peptide corresponding to Mouse CD271 aa 91-140 / 427 mouse.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
F9 cell lysate, PC-12 cell lysate, RAW264.7 cell lysate, L6.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IF-Cell: 1:50
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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