Transmembrane protein 2 Rabbit Polyclonal Antibody
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
KIAA1412 antibody TMEM 2 antibody tmem2 antibody TMEM2_HUMAN antibody Transmembrane protein 2 antibody
Abbreviation
TMEM2
Swiss Prot
Q9UHN6 Human, Q5FWI3 Mouse
Cellular Locus
Cell membrane. Membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Transmembrane protein 2 aa 98-147 / 1,383.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Mouse heart tissue, rat kidney tissue, human liver tissue, mouse liver tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 154 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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