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Transmembrane protein 2 Rabbit Polyclonal Antibody

Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

KIAA1412 antibody TMEM 2 antibody tmem2 antibody TMEM2_HUMAN antibody Transmembrane protein 2 antibody

Abbreviation

TMEM2

Swiss Prot

Q9UHN6 Human, Q5FWI3 Mouse

Cellular Locus

Cell membrane. Membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human Transmembrane protein 2 aa 98-147 / 1,383.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Mouse heart tissue, rat kidney tissue, human liver tissue, mouse liver tissue, mouse kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 154 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Curated Selection

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