Beta-2 Microglobulin Rabbit Polyclonal Antibody
β2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on almost all cells of the body. β-2-Microglobulin associates with the α heavy chain of MHC and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
B2M
Swiss Prot
P61769 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Beta-2 Microglobulin aa 21-70.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HL-60 cells.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:200 ;FC: 1:50
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
13 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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