Beta III Tubulin Rabbit Polyclonal Antibody
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and maintenance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Plays a role in dorsal root ganglion axon projection towards the spinal cord.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
TUBB3
Swiss Prot
Q13509 Human, Q9ERD7 Mouse, Q4QRB4 Rat
Cellular Locus
Cytoplasm. Cytoskeleton. Microtubule, Cell projection.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within N-terminal Human Neuron-specific class Ⅲ β-tubulin.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Hela cell lysate, HepG2, NIH/3T3, rat brain tissue, rat kidney tissue, human colon cancer tissue.
Concentration
1 mg/mL
Dilution
WB: 1:5,000-1:10,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:100-1:400 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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