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CD127 Rabbit Polyclonal Antibody

The IL-7 cytokine plays a major role in the in vivo maintenance of polyclonal naive and memory T cells, positively regulating the survival, differentiation and proliferation of thymocyte and peripheral T lymphocyte populations. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor γ chain common to the IL-2, IL-4,IL-7, IL-9 and IL-15 receptors. Soluble forms of the IL-7 Rα have been reported.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

CD 127 antibody CD127 antibody CD127 antigen antibody CDw127 antibody IL 7R alpha antibody IL 7R antibody IL-7 receptor subunit alpha antibody IL-7R subunit alpha antibody IL-7R-alpha antibody IL-7RA antibody IL7R antibody IL7RA antibody IL7RA_HUMAN antibody IL7Ralpha antibody ILRA antibody Interleukin 7 receptor alpha chain antibody Interleukin 7 receptor antibody Interleukin 7 receptor isoform H5 6 antibody Interleukin-7 receptor subunit alpha antibody

Abbreviation

IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA

Swiss Prot

P16871 Human

Cellular Locus

Secretion protein, Cell membrane, cytosol, nucleoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human IL-7R-alpha aa 13-62 / 459.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

K562 cell lysate, human skin tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-5,000;IHC-P: 1:200;IF-Cell: 1:50;FC: 1:50

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 52 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No

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