CD127 Rabbit Polyclonal Antibody
The IL-7 cytokine plays a major role in the in vivo maintenance of polyclonal naive and memory T cells, positively regulating the survival, differentiation and proliferation of thymocyte and peripheral T lymphocyte populations. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor γ chain common to the IL-2, IL-4,IL-7, IL-9 and IL-15 receptors. Soluble forms of the IL-7 Rα have been reported.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA
Swiss Prot
P16871 Human
Cellular Locus
Secretion protein, Cell membrane, cytosol, nucleoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human IL-7R-alpha aa 13-62 / 459.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
K562 cell lysate, human skin tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-5,000;IHC-P: 1:200;IF-Cell: 1:50;FC: 1:50
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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