GM-CSF-R-alpha (CD116) Rabbit Polyclonal Antibody
The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating factor, which stimulates the production of white blood cells. In contrast to M-CSF and G-CSF which are lineage specific, GM-CSF and its receptor play a role in earlier stages of development. The receptor is primarily located on neutrophils, eosinophils and monocytes/macrophages, it is also on CD34+ progenitor cells (myeloblasts) and precursors for erythroid and megakaryocytic lineages, but only in the beginning of their development. It is associated with Surfactant metabolism dysfunction type 4.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha
Swiss Prot
Q00941 Mouse
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Synthetic peptide within mouse GM-CSF-R-alpha (CD116) aa 11-60 / 388.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
F9 cell lysates.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:100-1:200;FC: 1:10-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 42 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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