c-kit Rabbit Polyclonal Antibody
CD117 Antigen, also called KIT or C-kit receptor, is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SCFR,PBT
Swiss Prot
P10721 Human
Cellular Locus
Cytoplasm, membrane
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human c-kit aa 109-150.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
Jurkat
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 110 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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