JJC8-088
Product Specifications
UNSPSC Description
JJC8-088 is a potent inhibitor of DAT. JJC8-088 is a novel Modafinil-derived ligands. JJC8-088 can be used to study psychostimulant use disorders[1].
Target Antigen
Dopamine Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jjc8-088.html
Solubility
10 mM in DMSO
Smiles
O=S(C(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)CCN3CCN(CC3)CC(CC4=CC=CC=C4)O
Molecular Weight
498.63
References & Citations
[1]Tunstall BJ, et al. Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats. Neuropharmacology. 2018 Mar 15;131:96-103. |[2]Newman AH, et al. Translating the atypical dopamine uptake inhibitor hypothesis toward therapeutics for treatment of psychostimulant use disorders. Neuropsychopharmacology. 2019 Jul;44(8):1435-1444.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158013/JJC8-088-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158013/
Clinical Information
No Development Reported
CAS Number
1627576-82-2
Curated Selection
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