JJC8-088
JJC8-088, a Modafinil-derived ligand, is a dopamine transporter (DAT) inhibitor with a Ki of 2.53 nM. JJC8-088 dioxalate can be to study psychostimulant use disorders[1][2].
Product Specifications
CAS Number
1627576-82-2
UNSPSC
12352005
Target
Dopamine Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jjc8-088.html
Solubility
10 mM in DMSO
Smiles
O=S(C(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)CCN3CCN(CC3)CC(CC4=CC=CC=C4)O
Molecular Formula
C28H32F2N2O2S
Molecular Weight
498.63
References & Citations
[1]Tunstall BJ, et al. Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats. Neuropharmacology. 2018 Mar 15;131:96-103. |[2]Newman AH, et al. Translating the atypical dopamine uptake inhibitor hypothesis toward therapeutics for treatment of psychostimulant use disorders. Neuropsychopharmacology. 2019 Jul;44 (8) :1435-1444.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
PC1008439-01 10 mg
2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine
Sign In for Pricing
View Details PC1008439-02 50 mg
2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine
Sign In for Pricing
View Details PC1008439-03 100 mg
2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine
Sign In for Pricing
View Details PC1008439-04 250 mg
2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine
Sign In for Pricing
View Details PC1008439-05 500 mg
2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine
Sign In for Pricing
View Details PC1008439-06 1 g
2-Chloro-4-[3-chloro-5- (trifluoromethyl) pyridin-2-ylthio]-5-fluoropyrimidine
Sign In for Pricing
View Details