Tropolone
Tropolone is a seven-membered non-benzenoid aromatic compound, which is the precursor of many Azulene derivatives. Tropolone is a potent mushroom tyrosinase inhibitor with an IC50 value of 0.4 μM. Its inhibitory effect can be achieved by dialysis or excess CU2+ Reversa. Tropolone exhibits broad anti-viral and anti-fungal activity and is synergistic upon co-treatment with nucleos (t) ide analog drugs. Tropolone is a promising candidate for research in osteosarcoma[1][2][3][4].
Product Specifications
CAS Number
533-75-5
UNSPSC
12352005
Hazard Statement
H314, H317, H410
Target
Fungal; Tyrosinase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tropolone.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : ≥ 100 mg/mL|H2O : 25 mg/mL (ultrasonic)
Smiles
O=C1C(O)=CC=CC=C1
Molecular Formula
C7H6O2
Molecular Weight
122.12
Precautions
H314, H317, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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