Anti-BCAS1 / NABC1 Antibody

Rabbit Polyclonal Antibody specific to BCAS1/NABC1

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Amplified and overexpressed in breast cancer, Novel amplified in breast cancer 1

Gene Name

BCAS1

NCBI Gene ID

UniProt

O75363

Cellular Locus

Cytoplasm

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids 532-550 of human BCAS1/NABC1.

Target Antigen

Breast carcinoma-amplified sequence 1

Target

BCAS1 / NABC1

Clonality

Polyclonal

Type

Antibody

Applications

WB, IHC

Field of Research

Cancer research

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Required for myelination. {UniProtKB:Q80YN3}.

Additionnal Information

Immunoblotting : use at 1-5ug/mL.A band of approximately 60kDa is detected, however, protein dimerization may occur. <br><br>These are recommended concentrations. User should determine optimal concentrations for their applications.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human BCAS1/NABC1.

Formulation

PBS, pH 7.4.

Buffer pH

pH 7.4

Target Background

Breast Carcinoma Amplified Sequence 1 (BCAS1), also known as Novel Amplified in Breast Cancer 1 (NABC1) was isolated from a region at 20q13 and is amplified in several tumor types. It is associated with more aggressive tumor phenotypes. BCAS1/NABC1 is highly expressed in some, but not all, breast cancer cell lines and in some breast tumors at 20q13.2. The BCAS1/NABC1 gene is predicted to encode a protein of 584 amino acids with no significant homology to other proteins.