PF-9363

PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer[1][2].

Product Specifications

CAS Number

[2569009-58-9]

Product Name Alternative

CTx-648

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Histone Acetyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pf-9363.html

Purity

99.64

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=S(C1=C(OC)C=CC=C1OC)(NC2=NOC3=C2C(OC)=CC(CN4N=CC=C4)=C3)=O

Molecular Formula

C20H20N4O6S

Molecular Weight

444.46

Precautions

H302, H315, H319

References & Citations

[1]Shikhar S, et al. First-in-class KAT6A/KAT6B Inhibitor CTx-648 (PF-9363) Demonstrates Potent Anti-tumor Activity in ER+ Breast Cancer with KAT6A Dysregulation|[2]WO2020254946

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MOZ/MORF

Available Sizes

Curated Selection

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