PF-9363
PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer[1][2].
Product Specifications
CAS Number
[2569009-58-9]
Product Name Alternative
CTx-648
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pf-9363.html
Purity
99.64
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(C1=C(OC)C=CC=C1OC)(NC2=NOC3=C2C(OC)=CC(CN4N=CC=C4)=C3)=O
Molecular Formula
C20H20N4O6S
Molecular Weight
444.46
Precautions
H302, H315, H319
References & Citations
[1]Shikhar S, et al. First-in-class KAT6A/KAT6B Inhibitor CTx-648 (PF-9363) Demonstrates Potent Anti-tumor Activity in ER+ Breast Cancer with KAT6A Dysregulation|[2]WO2020254946
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MOZ/MORF
Available Sizes
Curated Selection
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