Perfluorodecanoic acid
Product Specifications
UNSPSC Description
Perfluorodecanoic acid (PFDA) is a perfluoroalkyl substance (PFAS). Perfluorodecanoic acid induces weight loss and increases liver weight and lipid content in mice. Perfluorodecanoic acid also reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver[1][2].
Target Antigen
Caspase; Interleukin Related
Type
Reference compound
Related Pathways
Apoptosis;Immunology/Inflammation
Field of Research
Metabolic Disease
Purity
98.0
Smiles
C(=O)(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O
Molecular Weight
514.08
References & Citations
[1]Olson CT, et al. The acute toxicity of perfluorooctanoic and perfluorodecanoic acids in male rats and effects on tissue fatty acids. Toxicol Appl Pharmacol. 1983 Sep 30;70(3):362-72. |[2]Harris MW, et al. Developmental toxicity of perfluorodecanoic acid in C57BL/6N mice. Fundam Appl Toxicol. 1989 Apr;12(3):442-8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Clinical Information
No Development Reported
CAS Number
335-76-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6185767-01 0.1 mL
SMAD7 (SMAD Family Member 7, CRCS3, FLJ16482, MADH7, MADH8) (PE)
Ask
View Details MBS6185767-02 5x 0.1 mL
SMAD7 (SMAD Family Member 7, CRCS3, FLJ16482, MADH7, MADH8) (PE)
Ask
View Details