5-Lipoxygenase from Potato (5-LO)

<strong>5-Lipoxygenase from Potato (5-LO)</strong>_x000D_ <strong>Catalog number:</strong> B2013012_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 85 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 5-LO, 5-LOX_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wang S, Huai J, Shang Y, Xie L, Cao X, Liao J, Zhang T, Dai R. Screening for natural inhibitors of 5-lipoxygenase from Zi-shen pill extract by affinity ultrafiltration coupled with ultra performance liquid chromatography-mass spectrometry J Ethnopharmacol. 2020 May 23;254:112733._x000D_ 2: Rudhard Y, Sengupta Ghosh A, Lippert B, Böcker A, Pedaran M, Krämer J, Ngu H, Foreman O, Liu Y, Lewcock JW. Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening J Neurosci. 2015 Feb 18;35(7):2927-41._x000D_ 3: Nair DG, Funk CD. A cell-based assay for screening lipoxygenase inhibitors Prostaglandins Other Lipid Mediat. 2009 Dec;90(3-4):98-104._x000D_ 4: Dey R, Dey S, Samadder A, Saxena AK, Nandi S. Natural Inhibitors against Potential Targets of Cyclooxygenase, Lipoxygenase and Leukotrienes Comb Chem High Throughput Screen. 2022;25(14):2341-2357._x000D_ 5: Dahlström M, Forsström D, Johannesson M, Huque-Andersson Y, Björk M, Silfverplatz E, Sanin A, Schaal W, Pelcman B, Forsell PK. Development of a fluorescent intensity assay amenable for high-throughput screening for determining 15-lipoxygenase activity J Biomol Screen. 2010 Jul;15(6):671-9._x000D_ 6: Chen S, Zou H. Key Role of 12-Lipoxygenase and Its Metabolite 12-Hydroxyeicosatetraenoic Acid (12-HETE) in Diabetic Retinopathy Curr Eye Res. 2022 Mar;47(3):329-335._x000D_ 7: Rodrigues T, Bernardes GJL. Machine learning for target discovery in drug development Curr Opin Chem Biol. 2020 Jun;56:16-22._x000D_ 8: Heshof R, de Graaff LH, Villaverde JJ, Silvestre AJ, Haarmann T, Dalsgaard TK, Buchert J. Industrial potential of lipoxygenases Crit Rev Biotechnol. 2016 Aug;36(4):665-74._x000D_ 9: Parker AR, Ayars AG, Altman MC, Henderson WR Jr. Lipid Mediators in Aspirin-Exacerbated Respiratory Disease Immunol Allergy Clin North Am. 2016 Nov;36(4):749-763._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23953428">10: Steinhilber D, Hofmann B. Recent advances in the search for novel 5-lipoxygenase inhibitors Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):70-7. </a>_x000D_ _x000D_ <strong>Products Related to 5-Lipoxygenase from Potato (5-LO) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>