Lumateperone-13C, d3 (tosylate)
Lumateperone-13C, d3 (ITI-007-13C, d3) tosylate is 13C and deuterium labeled Lumateperone (tosylate) . Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia[1][2][3][4].
Product Specifications
Product Name Alternative
ITI-007-13C, d3 (tosylate)
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Smiles
O=C(CCCN1C[C@@]([H])(C2=CC=CC3=C2N4CCN3[13C]([2H])([2H])[2H])[C@]4([H])CC1)C5=CC=C(F)C=C5.CC6=CC=C(C=C6)S(O)(=O)=O
Molecular Formula
C30 13CH33D3FN3O4S
Molecular Weight
569.71
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Frequently Asked Questions
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