Antileishmanial agent-26
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with anti-Leishmania donovani activity. Its IC50 value against Leishmania donovani is 5.67 μM, and its CC50 value against THP-1 is 3.79 μM. Antileishmanial agent-26 can be used in the research of tropical diseases[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-26.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(N(C)C)N=C(NCC3=CC=C(F)C=C3)N=C2C=C1OC4CCCC4
Molecular Formula
C23H27FN4O2
Molecular Weight
410.48
References & Citations
[1]Das N, et al. Hit-to-lead optimization of 2-aminoquinazolines as anti-microbial agents against Leishmania donovani[J]. European Journal of Medicinal Chemistry, 2024: 116256.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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