GW695634
Product Specifications
UNSPSC Description
GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses[1].
Target Antigen
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gw695634.html
Smiles
CCC(NS(=O)(C1=CC=C(C(C)=C1)NC(COC2=CC=C(C=C2C(C3=CC(C#N)=CC(Cl)=C3)=O)Cl)=O)=O)=O
Molecular Weight
574.43
References & Citations
[1]M de Serres, et al. "The disposition and metabolism of GW695634: a non-nucleoside reverse transcriptase inhibitor (NNRTi) for treatment of HIV/AIDS." Xenobiotica 40.6 (2010): 437-445.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123330/GW695634-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123330/
Clinical Information
Phase 1
CAS Number
457635-65-3
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