Acetyl- (D-Arg2) -GRF (1-29) amide (human)

Acetyl- (D-Arg2) -GRF (1-29) amide (human) is an antagonist of growth hormone releasing factor (GRF) . Acetyl- (D-Arg2) -GRF (1-29) amide (human) inhibits the release of growth hormone (GH) and can be used for endocrine research[1].

Product Specifications

CAS Number

[93942-91-7]

UNSPSC

12352209

Target

GHSR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/acetyl-d-arg2-grf-1-29-amide-human.html

Purity

99.67

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@H](NC(C)=O)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCSC)C(N[C@@H](CO)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O

Molecular Formula

C154H255N47O43S

Molecular Weight

3485.03

References & Citations

[1]Lumpkin MD, et al. Blockade of growth hormone-releasing factor (GRF) activity in the pituitary and hypothalamus of the conscious rat with a peptidic GRF antagonist. Endocrinology. 1989 Mar;124 (3) :1522-31.