Scyliorhinin I
Product Specifications
UNSPSC Description
Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a Ki value of 0.9 nM for rat submandibular gland NK-1 receptor and 2 nM for hamster bladder NK-2 receptor. Scyliorhinin I has the ability to contract the longitudinal muscles of the guinea pig ileum[1][2].
Target Antigen
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/scyliorhinin-i.html
Smiles
OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC([C@@H](N)C)=O)CCCCN)=O)CC2=CC=CC=C2)=O)=O)=O)CC3=CC=CC=C3)=O
Molecular Weight
1218.47
References & Citations
[1]Conlon, et al. "Scyliorhinin I and II: two novel tachykinins from dogfish gut." FEBS letters 200.1 (1986): 111-116.|[2]Stephen H, et al. "The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors." European journal of pharmacology 144.1 (1987): 109-111.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10599/Scyliorhinin-I-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10599/
Clinical Information
No Development Reported
CAS Number
103425-21-4
Curated Selection
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