Elaiophylin

Elaiophylin (Azalomycin B; Gopalamicin; Efomycin E) is an autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells[1].

Product Specifications

CAS Number

[37318-06-2]

Product Name Alternative

Azalomycin B; Gopalamicin; Efomycin E

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Antibiotic; Autophagy

Type

Reference compound

Related Pathways

Anti-infection; Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Elaiophylin.html

Purity

98.0

Solubility

DMSO : 20 mg/mL (ultrasonic; warming)

Smiles

C[C@H]1[C@@H](O)[C@@H](O)C[C@H](O[C@@H]2C[C@@]([C@H]([C@H](O)[C@H](C)[C@](OC(/C=C/C=C/[C@H](C)[C@]([C@@H](C)[C@@H](O)[C@@H]([C@]3(O)O[C@H](C)[C@@H](CC)[C@H](O[C@H]4C[C@H](O)[C@H](O)[C@H](C)O4)C3)C)([H])OC5=O)=O)([H])[C@H](/C=C/C=C/5)C)C)(O)O[C@H](C)[C@H]2CC)O1

Molecular Formula

C54H88O18

Molecular Weight

1025.27

Precautions

H302+H312+H332

References & Citations

[1]Zhao X, et al Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells. Autophagy. 2015;11 (10) :1849-63.