Schisandronic acid
Schisandronic acid is a triterpenoid antioxidant and anticancer agent extracted from Schisandra chinensis, which has potent cytotoxicity against human breast cancer cells, especially MCF-7. Schisandronic acid induces apoptosis and reduces cell viability in a time-dependent manner (MCF-7, IC50=8.06 μM) . Schisandronic acid can upregulate active caspase-3 expression and cleave PARP, reduce the generation of reactive oxygen species and exhibit antioxidant effects[1].
Product Specifications
CAS Number
55511-14-3
Product Name Alternative
Ganwuweizic acid
UNSPSC
12352211
Target
Apoptosis; PARP
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/schisandronic-acid.html
Smiles
C[C@H](CC/C=C(C)\C(O)=O)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@H]4C(C(CC[C@@]45C[C@@]35CC[C@]12C)=O)(C)C
Molecular Formula
C30H46O3
Molecular Weight
454.68
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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