CGP 53820

CGP 53820 is an inhibitor for HIV protease, inhibits the complex of HIV-1 and HIV-2 protease with Ki of 9 and 53 nM for HIV-1 protease and HIV-2 protease. CGP 53820 can be used in AIDS research[1].

Product Specifications

CAS Number

[149267-24-3]

UNSPSC

12352005

Target

HIV; HIV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cgp-53820.html

Smiles

CC(C)[C@@H](C(NN(C[C@H](O)[C@@H](NC([C@@H](NC(C)=O)C(C)C)=O)CC1=CC=CC=C1)CC2CCCCC2)=O)NC(C)=O

Molecular Formula

C31H51N5O5

Molecular Weight

573.77

References & Citations

[1]Priestle JP, et al., Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor. Structure. 1995 Apr 15;3 (4) :381-9.