PRKX Protein Active
<strong>PRKX Protein Active</strong>_x000D_ <strong>Catalog number:</strong> B2013975_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 44.7 kDa_x000D_ <strong>Supplied as:</strong> N/A_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> PRKX Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Huang S, Li Q, Alberts I, Li X. PRKX, a Novel cAMP-Dependent Protein Kinase Member, Plays an Important Role in Development J Cell Biochem. 2016 Mar;117(3):566-73._x000D_ 2: Li X, Burrow CR, Polgar K, Hyink DP, Gusella GL, Wilson PD. Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency Biochim Biophys Acta. 2008 Jan;1782(1):1-9._x000D_ 3: Zimmermann B, Chiorini JA, Ma Y, Kotin RM, Herberg FW. PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I J Biol Chem. 1999 Feb 26;274(9):5370-8._x000D_ 4: Li X, Li HP, Amsler K, Hyink D, Wilson PD, Burrow CR. PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9260-5._x000D_ 5: Chiorini JA, Zimmermann B, Yang L, Smith RH, Ahearn A, Herberg F, Kotin RM. Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2 Mol Cell Biol. 1998 Oct;18(10):5921-9._x000D_ 6: Diskar M, Zenn HM, Kaupisch A, Kaufholz M, Brockmeyer S, Sohmen D, Berrera M, Zaccolo M, Boshart M, Herberg FW, Prinz A. Regulation of cAMP-dependent protein kinases: the human protein kinase X (PrKX) reveals the role of the catalytic subunit alphaH-alphaI loop J Biol Chem. 2010 Nov 12;285(46):35910-8._x000D_ 7: Glesne D, Huberman E. Smad6 is a protein kinase X phosphorylation substrate and is required for HL-60 cell differentiation Oncogene. 2006 Jul 6;25(29):4086-98._x000D_ 8: Di Pasquale G, Stacey SN. Adeno-associated virus Rep78 protein interacts with protein kinase A and its homolog PRKX and inhibits CREB-dependent transcriptional activation J Virol. 1998 Oct;72(10):7916-25._x000D_ 9: Ouyang C, Nie L, Gu M, Wu A, Han X, Wang X, Shao J, Xia Z. Transforming growth factor (TGF)-_-activated kinase 1 (TAK1) activation requires phosphorylation of serine 412 by protein kinase A catalytic subunit (PKAC) and X-linked protein kinase (PRKX) J Biol Chem. 2014 Aug 29;289(35):24226-37._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/16236808">10: Li X, Hyink DP, Polgar K, Gusella GL, Wilson PD, Burrow CR. Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney J Am Soc Nephrol. 2005 Dec;16(12):3543-52. </a>_x000D_ _x000D_ <strong>Products Related to PRKX Protein Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>
Product Specifications
Short Description
Catalog Number: B2013975 (10 µg)
Weight
0.15
Length
2
Width
0.5
Height
0.5
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