(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate)
Product Specifications
UNSPSC Description
(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate) is an antagonist for Substance P (HY-P0201) and Bombesin (HY-P0195) that has effects on ocular inflammatory responses to antidromic trigeminal nerve stimulation[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-arg1-d-pro2-d-trp7-9-l-leu11-substance-p-acetate.html
Solubility
10 mM in DMSO
Smiles
C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC(=O)[C@@H]5N(C([C@@H](CCCNC(=N)N)N)=O)CCC5)CCCCN)=O)CCC4)CCC(N)=O)=O)CCC(N)=O)=O)C=6C=7C(NC6)=CC=CC7.xC(C)(O)=O
Molecular Weight
1497.79 (free base)
References & Citations
[1]A Mandahl, A Bill, et al. Effects of the substance P antagonist, (D-Arg1, D-Pro2, D-Trp7,9, Leu11)-SP on the miotic response to substance P, antidromic trigeminal nerve stimulation, capsaicin, prostaglandin E1, compound 48/80 and histamine. Acta Physiol Scand. 1984 Jan;120(1):27-35.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3225/D-Arg1-D-Pro2-D-Trp7-9-L-Leu11-Substance-P-acetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3225/
Clinical Information
No Development Reported
CAS Number
143077-65-0
Curated Selection
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