MASP1, Human (HEK293, His)

MASP1 Protein, Human (HEK293, His) is a recombinant human Mannan-binding lectin serine protease 1 produced in HEK293 cells, with a His tag at the C-terminus. Mannan-binding lectin serine protease 1 is a serine protease associated with humoral pattern-recognition molecules[1].

HTVELNNMFG QIQSPGYPDS YPSDSEVTWN ITVPDGFRIK LYFMHFNLES SYLCEYDYVK VETEDQVLAT FCGRETTDTE QTPGQEVVLS PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN YIGGYYCSCR FGYILHTDNR TCRVECSDNL FTQRTGVITS PDFPNPYPKS SECLYTIELE EGFMVNLQFE DIFDIEDHPE VPCPYDYIKI KVGPKVLGPF CGEKAPEPIS TQSHSVLILF HSDNSGENRG WRLSYRAAGN ECPELQPPVH GKIEPSQAKY FFKDQVLVSC DTGYKVLKDN VEMDTFQIEC LKDGTWSNKI PTCKIVDCRA PGELEHGLIT FSTRNNLTTY KSEIKYSCQE PYYKMLNNNT GIYTCSAQGV WMNKVLGRSL PTCLPECGQP SRSLPSLVKR IIGGRNAEPG LFPWQALIVV EDTSRVPNDK WFGSGALLSA SWILTAAHVL RSQRRDTTVI PVSKEHVTVY LGLHDVRDKS GAVNSSAARV VLHPDFNIQN YNHDIALVQL QEPVPLGPHV MPVCLPRLEP EGPAPHMLGL VAGWGISNPN VTVDEIISSG TRTLSDVLQY VKLPVVPHAE CKTSYESRSG NYSVTENMFC AGYYEGGKDT CLGDSGGAFV IFDDLSQRWV VQGLVSWGGP EECGSKQVYG VYTKVSNYVD WVWEQMGLPQ SVVEPQVERH HHHHH

[1]Thiel S, et al. Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine proteaseassociated with humoral pattern-recognition molecules: normal and acute-phase levels in serumand stoichiometry of lectin pathway components. Clin Exp Immunol. 2012 Jul;169(1):38-48.|[2]Dobó J, et al. MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basisof its broad specificity. J Immunol. 2009 Jul 15;183(2):1207-14.