Cyclo (-RGDfK)
Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM[1]. Cyclo (-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[2].
Product Specifications
CAS Number
161552-03-0
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Cyclo_-RGDfK_.html
Purity
99.83
Solubility
DMSO : 83.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=C([C@H](CCCCN)NC([C@@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CN2)=O)=O)=O)N[C@@H](CCCNC(N)=N)C2=O
Molecular Formula
C27H41N9O7
Molecular Weight
603.67
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
αvβ3
Citation 01
Available Sizes
Frequently Asked Questions
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