Valziflocept

Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor that targets Fc and FcγR. FcγRs bind and neutralize pathogenic IgG, thus forming a "decoy" or "scavenger" receptor that can reduce the severity of autoimmune diseases. Valziflocept can be used in studies of autoimmune diseases such as systemic lupus erythematosus (SLE) [1].

Product Specifications

CAS Number

[1804910-11-9]

Product Name Alternative

BAX1810; TAK-752

UNSPSC

12352203

Target

Fc Receptor (FcR)

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/valziflocept.html

Purity

99.00

Solubility

10 mM in DMSO

Smiles

[Valziflocept]

Molecular Weight

(19.693 kDa)

References & Citations

[1]Adrian W Zuercher, et al. Next-generation Fc receptor-targeting biologics for autoimmune diseases. Autoimmun Rev. 2019 Oct;18 (10) :102366.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-74409G 0.1 mL

Mouse Monoclonal SUHW1 Antibody (OTI2H3) [DyLight 488]

Ask

View Details

NBP2-97288PE 0.1 mL

Rabbit Polyclonal OS9 Antibody [PE]

Ask

View Details

abx979143-01 150 µg

Mouse NLRP4C shRNA Plasmid

Ask

View Details

abx979143-02 300 µg

Mouse NLRP4C shRNA Plasmid

Ask

View Details

MBS960796-01 0.02 mg (E-Coli)

Recombinant Human DNA-directed RNA polymerase II subunit RPB9 (POLR2I)

Ask

View Details

MBS960796-02 0.1 mg (E-Coli)

Recombinant Human DNA-directed RNA polymerase II subunit RPB9 (POLR2I)

Ask

View Details