Fluorescein-12-dATP
Fluorescein-12-dATP is a fluorescent dye acting as the detection probe. Fluorescein-12-dATP can be used to label the thrombin-binding aptamers by catalytic polymerization of TdT (terminal deoxynucleotidyl transferase) [1]. Fluorescein-12-dATP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fluorescein-12-datp.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC#CC1=CN(C2=C1C(N)=NC=N2)[C@@]3(O[C@@H]([C@H](C3)O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[H])CCCCCNC(C4=CC=C(C(C(O)=O)=C4)C5=C(C(OC6=C5C=CC(O)=C6)=C7)C=CC7=O)=O
Molecular Formula
C41H41N6O19P3
Molecular Weight
1014.71
References & Citations
[1]Wen D, et al. Highly sensitive fluorometric determination of thrombin by on-chip signal amplification initiated by terminal deoxynucleotidyl transferase. Mikrochim Acta. 2018 Jul 19;185 (8) :380.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Curated Selection
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