CLinDMA

CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA[1].

Product Specifications

CAS Number

[908860-82-2]

UNSPSC

12352211

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/clindma.html

Purity

99.89

Solubility

DMSO : 140 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OCCCCOC(CN(C)C)COCCCCCCCC/C=C\C/C=C\CCCCC)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C

Molecular Formula

C54H97NO3

Molecular Weight

808.35

References & Citations

[1]Abrams MT, et al. Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment. Mol Ther. 2010;18 (1) :171-180.