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Lipopolysaccharides, from S. enterica serotype typhimurium

Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium are lipopolysaccharide endotoxins and TLR4 activators derived from serotype typhimurium of Salmonella enterica, and are classified as S-type LPS. Lipopolysaccharides, from S. enterica exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from S. enterica serotype typhimurium can modulate the fate of bacteria in dendritic cells (DC), determining the uptake, degradation, and activation of immune functions by DC cells against the bacteria[1][2][3][4]. It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.

Product Specifications

Product Name Alternative

LPS, from Salmonella enterica (Serotype typhimurium)

UNSPSC

12352200

Target

Toll-like Receptor (TLR)

Type

Biochemical Assay Reagents

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lipopolysaccharides-from-s-enterica-serotype-typhimurium.html

Smiles

[Lipopolysaccharides,fromS.entericaserotypetyphimurium]

References & Citations

[1]Cryz SJ Jr, et al. Role of lipopolysaccharide in virulence of Pseudomonas aeruginosa. Infect Immun. 1984 May;44 (2) :508-13.|[2]Murray G L, et al. Altering the length of the lipopolysaccharide O antigen has an impact on the interaction of Salmonella enterica serovar Typhimurium with macrophages and complement[J]. Journal of bacteriology, 2006, 188 (7) : 2735-2739.|[3]Zenk SF, et al. Role of Salmonella enterica lipopolysaccharide in activation of dendritic cell functions and bacterial containment. J Immunol. 2009 Aug 15;183 (4) :2697-707.|[4]Heinrichs DE, et al. Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica. Mol Microbiol. 1998 Oct;30 (2) :221-32.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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