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Human DRD2 Protein, Flag, His Tag (Detergent)

Human DRD2 Protein, Flag, His Tag (DR2-H52D3) is expressed from human 293 cells (HEK293) . It contains AA Asn 35 - Arg 222 & Lys 362 - Cys 443 (Accession # P14416-1) .

Product Specifications

Background

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Specifications

This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.3 kDa.

Accession Number

P14416-1

Expression Region

Asn 35 - Arg 222 & Lys 362 - Cys 443

Host

HEK293

Target

DRD2

Conjugation

Unconjugated

Tag

N-Flag & C-10xHis

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5

Additives

Glycerol

Molecular Weight

48.3 kDa

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

20ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/DR2-H52D3.pdf

Species

Human

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