GSK 2837808A

1445879-21-9

3-((3-(N-cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid

Metabolism Dehydrogenase

0.98

A crystalline solid

≥9.12 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O

O=S(C(C=N1)=C(NC2=CC(OC3=CC(F)=CC(F)=C3)=CC(C(O)=O)=C2)C(C1=C4)=CC=C4C5=CN=C(OC)N=C5OC)(NC6CC6)=O

C31H25F2N5O7S

649.62

Blue ice

Store at -20°C.