Lgr5/GPR49, Human (HEK293, hFc)
The Lgr5/GPR49 protein is a receptor for R-spondins that enhances the canonical Wnt signaling pathway and marks stem cells in the intestinal epithelium and hair follicles. Lgr5/GPR49 binds R-spondins (RSPO1-4), binds to phosphorylated LRP6 and Frizzled receptors, initiates Wnt signaling and amplifies target gene expression. Lgr5/GPR49 Protein, Human (HEK293, hFc) is the recombinant human-derived Lgr5/GPR49 protein, expressed by HEK293 , with C-hFc labeled tag.
Product Specifications
Product Name Alternative
Lgr5/GPR49 Protein, Human (HEK293, hFc), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/lgr5-gpr49-protein-human-hek293-hfc.html
Molecular Formula
8549 (Gene_ID) O75473-1 (G22-P543) (Accession)
Molecular Weight
Approximately 110-120 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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