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Citric acid-d4

Product Specifications

UNSPSC Description

Citric acid-d4 is the deuterium labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer.

Target Antigen

Antibiotic; Apoptosis; Bacterial; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection;Apoptosis;Metabolic Enzyme/Protease

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Purity

98.0

Solubility

10 mM in DMSO

Smiles

OC(C([2H])([2H])C(C(O)=O)(O)C([2H])([2H])C(O)=O)=O

Molecular Weight

196.15

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20.|[3]Abdel-Salam OM, et al. Citric acid effects on brain and liver oxidative stress in lipopolysaccharide-treated mice. J Med Food. 2014 May;17(5):588-98.|[4]Lacour B, et al. Stimulation by citric acid of calcium and phosphorus bioavailability in rats fed a calcium-rich diet. Miner Electrolyte Metab. 1997;23(2):79-87.|[5]Nagai R, et al. Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats. Biochem Biophys Res Commun. 2010 Feb 26;393(1):118-22.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Clinical Information

No Development Reported

CAS Number

147664-83-3

Available Sizes

Curated Selection

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