OSI-420 free base

183321-86-0

2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol

OSI-420, Desmethyl Erlotinib, CP-473420

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

0.9846

insoluble in H2O; insoluble in EtOH; ≥51 mg/mL in DMSO

C#CC1=CC(NC2=NC=NC3=C2C=C(OCCO)C(OCCOC)=C3)=CC=C1

C21H21N3O4

379.41

Blue ice

Store at -20°C.