6-Phe-cAMP
6-Phe-cAMP is a site-selective and highly membrane-permeant activator of protein kinase A (PKA), with a strong preference for site A of both isozymes. 6-Phe-cAMP can undergo phosphorothioate modification[1].
Product Specifications
CAS Number
[34051-30-4]
Product Name Alternative
N6-Phenyladenosine-3',5'-cyclic monophosphate
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-phe-camp.html
Smiles
O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C=NC4=C3N=CN=C4NC5=CC=CC=C5
Molecular Formula
C16H16N5O6P
Molecular Weight
405.30
References & Citations
[1]Klöss S, et al. Down-regulation of soluble guanylyl cyclase expression by cyclic AMP is mediated by mRNA-stabilizing protein HuR. Mol Pharmacol. 2004 Jun;65 (6) :1440-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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