6-Phe-cAMP

6-Phe-cAMP is a site-selective and highly membrane-permeant activator of protein kinase A (PKA), with a strong preference for site A of both isozymes. 6-Phe-cAMP can undergo phosphorothioate modification[1].

Product Specifications

CAS Number

[34051-30-4]

Product Name Alternative

N6-Phenyladenosine-3',5'-cyclic monophosphate

UNSPSC

12352005

Target

PKA

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-phe-camp.html

Smiles

O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C=NC4=C3N=CN=C4NC5=CC=CC=C5

Molecular Formula

C16H16N5O6P

Molecular Weight

405.30

References & Citations

[1]Klöss S, et al. Down-regulation of soluble guanylyl cyclase expression by cyclic AMP is mediated by mRNA-stabilizing protein HuR. Mol Pharmacol. 2004 Jun;65 (6) :1440-51.