Cinchonine (hydrochloride)
Cinchonine hydrochloride ((8R,9S) -Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. Cinchonine hydrochloride activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells[1].
Product Specifications
CAS Number
5949-11-1
Product Name Alternative
(8R,9S) -Cinchonine (hydrochloride) ; LA40221 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Apoptosis; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cinchonine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
[H]Cl.O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3
Molecular Formula
C19H23ClN2O
Molecular Weight
330.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Plasmodium
Frequently Asked Questions
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