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Cefuroxime (sodium)

Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].

Product Specifications

CAS Number

[56238-63-2]

UNSPSC

12352005

Hazard Statement

H317

Target

Antibiotic; Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Cefuroxime-sodium.html

Purity

99.75

Solubility

DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O[Na]

Molecular Formula

C16H15N4NaO8S

Molecular Weight

446.37

Precautions

H317

References & Citations

[1]Callaghan, et al. Cefuroxime sodium, a New Cephalosporin Antibiotic: Activity in Vitro. Antimicrob Agents Chemother. 1976 Mar;9 (3) :511-9.|[2]D M Ryan, et al. Cefuroxime sodium, a New Cephalosporin Antibiotic: Activity in Vivo. Antimicrob Agents Chemother. 1976 Mar;9 (3) :520-5.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Citation 01

Biomed Res Int. 2018 Jul 2:2018:3579832.|Int J Antimicrob Agents. 2024 May 30:107229.|J Chem Inf Model. 2021 Apr 26;61 (4) :2016-2025.|Adv Funct Mater. 2024 Jun 19.|Diagn Microbiol Infect Dis. 2025 Nov 4;114 (2) :117181.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Nat Commun. 2023 Mar 22;14 (1) :1594.|University of Texas. 2025.

Available Sizes

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