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INCB8761(PF-4136309)

CCR2 Antagonist,potent and selective

Product Specifications

CAS Number

1341224-83-6

Product Name Alternative

N-(2-(3-((4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide

Sequence

INCB8761;PF-4136309;PF4136309;PF 4136309;INCB-8761

Field of Research

GPCR G protein CCR2

Purity

0.9836

Solubility

≥50.1 mg/mL in DMSO; ≥26.15 mg/mL in EtOH; insoluble in H2O

Smiles

O=C(CNC(C1=CC(C(F)(F)F)=CC=C1)=O)N(C2)CCC2NC3CCC(C4=NC=C(C5=NC=CC=N5)C=C4)(O)CC3

Molecular Formula

C29H31F3N6O3

Molecular Weight

568.59

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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